Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | USP2 | O75604 | 4/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813501 | 0.73 | KDM4E (0.34) | HDAC6CYP1A2ALDH1A1HSD17B10USP2 | |
| SCHEMBL20223112 | 0.72 | BRPF1 (0.40) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL21038298 | 0.72 | ALOX5 (0.35) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL30473131 | 0.72 | BRPF1 (0.40) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL13041958 | 0.71 | KDM4E (0.35) | HDAC6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL145694 | 0.69 | HDAC6 (0.40) | HDAC6ALDH1A1TSHRHDAC1GLA | |
| SCHEMBL21363502 | 0.69 | CLK4 (0.38) | HDAC6CYP1A2CYP2D6CYP3A4CLK4 | |
| SCHEMBL31532138 | 0.69 | CYP1A2 (0.53) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL21038063 | 0.69 | CYP1A2 (0.41) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL21038062 | 0.69 | PTGER4 (0.36) | CYP1A2ALDH1A1HSD17B10USP2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | HDAC6 883/4885CYP1A2 2035/4885ALDH1A1 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.