SCHEMBL35211618

SCHEMBL35211618

Nc1nc2ccnc(Cl)c2s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
PIK3CD O00329 5/20 0.38
PIK3CG P48736 5/20 0.38
PI4KA P42356 4/20 0.38
PI4KB Q9UBF8 4/20 0.38
PIK3CA P42336 4/20 0.38
PIP5K1C O60331 2/20 0.38
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
RAB9A P51151 2/20 0.36
AXL P30530 1/20 0.35
GFER P55789 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17200317 0.76 RAB9A (0.42) SMN1; SMN2ALDH1A1MAPTTP53HSD17B10
SCHEMBL22993546 0.75 ALDH1A1 (0.55) SMN1; SMN2ALDH1A1MAPTPIK3CDPIK3CG
SCHEMBL9676001 0.72 PSMB8 (0.56) SMN1; SMN2ALDH1A1MAPTHSD17B10RAB9A
SCHEMBL2069631 0.72 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1MAPTPI4KAPI4KB
SCHEMBL16835636 0.72 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTCYP3A4HSD17B10
SCHEMBL31726115 0.72 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTCYP3A4HSD17B10
SCHEMBL793886 0.71 TYK2 (0.50) SMN1; SMN2ALDH1A1MAPTRAB9AGAA
SCHEMBL793759 0.71 TYK2 (0.47) SMN1; SMN2ALDH1A1TP53CYP3A4HSD17B10
SCHEMBL21242832 0.71 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1MAPTCYP3A4HSD17B10
SCHEMBL34471500 0.71 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1MAPTCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNNA1, CTNND1 SMN1; SMN2 2898/4885ALDH1A1 1195/4885MAPT 4207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.