Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 4/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.31 |
| ▸ | CPS1 | P31327 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35212411 | 1.00 | CFD (0.34) | CFDEGFRCCR1ADAMTS5CPS1 | |
| SCHEMBL35212284 | 0.91 | SUV39H2 (0.34) | CFDCCR1ADAMTS5 | |
| SCHEMBL35211741 | 0.91 | SUV39H2 (0.34) | CFDCCR1ADAMTS5 | |
| SCHEMBL35212367 | 0.91 | CCR1 (0.32) | CFDCCR1 | |
| SCHEMBL35212137 | 0.91 | CCR1 (0.32) | CFDCCR1 | |
| SCHEMBL35211723 | 0.89 | CFD (0.32) | CFDCCR1 | |
| SCHEMBL35212289 | 0.89 | CFD (0.32) | CFDCCR1 | |
| SCHEMBL35211724 | 0.87 | CCR1 (0.32) | CFDCCR1ADAMTS5 | |
| SCHEMBL35212330 | 0.87 | CCR1 (0.32) | CFDCCR1ADAMTS5 | |
| SCHEMBL35212050 | 0.85 | SUV39H2 (0.35) | EGFRCCR1SRCDRD2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, PRKG1, GMPS | CFD 4697/4885EGFR 3537/4885CCR1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.