Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 15/20 | 0.45 |
| ▸ | CCND1 | P24385 | 15/20 | 0.45 |
| ▸ | CCND2 | P30279 | 15/20 | 0.45 |
| ▸ | CCND3 | P30281 | 15/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10245183 | 0.79 | CDK4 (0.51) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL29830392 | 0.79 | CDK4 (0.51) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL35212128 | 0.77 | CDK4 (0.35) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL22538172 | 0.77 | BTK (0.64) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL6641014 | 0.75 | BTK (0.58) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL17119621 | 0.75 | BTK (0.58) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL6640906 | 0.75 | BTK (0.61) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL1356214 | 0.75 | BRPF1 (0.53) | CDK4CCND1CCND2CCND3KDM4E | |
| SCHEMBL35211518 | 0.75 | BRPF1 (0.53) | CDK4CCND1CCND2CCND3KDM4E | |
| SCHEMBL3441071 | 0.73 | CA12 (0.57) | BTKCDK4CCND1CCND2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | BTK 171/4885CDK4 1531/4885CCND1 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.