SCHEMBL35212330

SCHEMBL35212330

[2H]C([2H])([2H])OC([2H])([2H])C(=O)N1C[C@H](C)n2nc3c(F)c(Cl)c(OC)cc3c2[C@H]1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 4/20 0.32
▸ CFD P00746 2/20 0.32
▸ ADAMTS5 Q9UNA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35211724 1.00 CCR1 (0.32) CCR1CFDADAMTS5
SCHEMBL35211720 0.92 CCR1 (0.31) CCR1
SCHEMBL35212033 0.92 CCR1 (0.31) CCR1
SCHEMBL35212284 0.88 SUV39H2 (0.34) CCR1CFDADAMTS5
SCHEMBL35211741 0.88 SUV39H2 (0.34) CCR1CFDADAMTS5
SCHEMBL35212616 0.87 CFD (0.34) CCR1CFDADAMTS5
SCHEMBL35212411 0.87 CFD (0.34) CCR1CFDADAMTS5
SCHEMBL35212289 0.84 CFD (0.32) CCR1CFD
SCHEMBL35211723 0.84 CFD (0.32) CCR1CFD
SCHEMBL34466325 0.82 PTGDR2 (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF CGAS, PRKG1, GMPS CCR1 930/4885CFD 4697/4885ADAMTS5 4519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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