SCHEMBL35212367

SCHEMBL35212367

COc1cc2c3n(nc2c(Cl)c1Cl)[C@@H](C)CN(C(=O)CO)[C@H]3C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 5/20 0.32
▸ CFD P00746 2/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35212137 1.00 CCR1 (0.32) CCR1CFDMEN1KMT2A
SCHEMBL35211354 0.92 ALDH1A1 (0.34) CCR1CFDMEN1KMT2A
SCHEMBL35212411 0.91 CFD (0.34) CCR1CFD
SCHEMBL35212616 0.91 CFD (0.34) CCR1CFD
SCHEMBL35211270 0.91 CFD (0.31) CCR1CFD
SCHEMBL35211430 0.91 CFD (0.31) CCR1CFD
SCHEMBL35211785 0.89 CCR1 (0.31) CCR1KMT2A
SCHEMBL35212589 0.89 CCR1 (0.31) CCR1KMT2A
SCHEMBL35212048 0.89 CCR1 (0.31) CCR1KMT2A
SCHEMBL35212567 0.88 SMN1; SMN2 (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF CGAS, PRKG1, GMPS CCR1 930/4885CFD 4697/4885MEN1 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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