⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318595 | 0.93 | CYP1A2 (0.32) | — | |
| SCHEMBL152508 | 0.91 | CYP1A2 (0.33) | — | |
| SCHEMBL2274793 | 0.88 | ALDH1A1 (0.40) | — | |
| SCHEMBL2270433 | 0.88 | ALDH1A1 (0.40) | — | |
| SCHEMBL15987646 | 0.83 | CYP1A2 (0.41) | — | |
| SCHEMBL385879 | 0.83 | METAP2 (0.38) | — | |
| SCHEMBL20773996 | 0.83 | HPRT1 (0.50) | — | |
| SCHEMBL20774140 | 0.83 | HPRT1 (0.50) | — | |
| SCHEMBL2448398 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL3783406 | 0.81 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349336-A1 | COMBINATION OF SUBSTITUTED 2,4 DIAMINO-QUINOLINE COMPOUNDS AND MEK INHIBITORS FOR USE IN THE TREATMENT OF LIVER CANCERS | Genoscience Pharma (FR) | 2024-04-10 | — | — | EP | disclosed |
| US-11261189-B2 | Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases | GENOSCIENCE PHARMA (FR) | 2022-03-01 | — | — | US | disclosed |
| EP-3846814-A1 | SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW MEDICAMENT FOR FIBROSIS, AUTOPHAGY AND CATHEPSINS B (CTSB), L (CTSL) AND D (CTSD) RELATED DISEASES | Genoscience Pharma (FR) | 2021-07-14 | — | — | EP | disclosed |
| EP-3452465-B1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2020-11-04 | — | — | EP | disclosed |
| US-20200079781-A1 | Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases | GENOSCIENCE PHARMA (FR) | 2020-03-12 | — | — | US | disclosed |
| EP-3620164-A1 | SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW MEDICAMENT FOR FIBROSIS, AUTOPHAGY AND CATHEPSINS B (CTSB), L (CTSL) AND D (CTSD) RELATED DISEASES | Genoscience Pharma SAS (FR) | 2020-03-11 | — | — | EP | disclosed |
| US-10586929-B2 | Solvent-resistant hole transport layers | LG CHEM, LTD. (KR) | 2020-03-10 | — | — | US | disclosed |
| US-10577362-B2 | Substituted 2, 4-diamino-quinoline derivatives for use in the treatment of proliferative diseases | GENOSCIENCE PHARMA (FR) | 2020-03-03 | — | — | US | disclosed |
| US-20190144437-A1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2019-05-16 | — | — | US | disclosed |
| EP-3452465-A1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | Genoscience Pharma SAS (FR) | 2019-03-13 | — | — | EP | disclosed |
| US-8497495-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-30 | — | — | US | disclosed |
| US-20120187382-A1 | ELECTRONIC DEVICES HAVING LONG LIFETIME | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
| US-20100252819-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | disclosed |
| US-7271406-B2 | Electron transport agents for organic electronic devices | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| EP-0152372-B1 | SUBSTITUTED UNSATURATED BICYCLIC IMIDES AND THEIR POLYMERS | CIBA-GEIGY AG (CH) | 1991-12-27 | — | — | EP | disclosed |
| EP-0152372-A2 | Substituted unsaturated bicyclic imides and their polymers | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | disclosed |