SCHEMBL3522157

SCHEMBL3522157

Cc1cc2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.40
▸ STAT1 P42224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958207 0.98 STAT3 (0.39) STAT3STAT1
SCHEMBL29881668 0.96 STAT3 (0.44) STAT3STAT1
SCHEMBL16922205 0.87 STAT3 (0.35) STAT3STAT1
Propionic Acid SCHEMBL28245922 0.87 STAT3 (0.35) STAT3STAT1
Propionic Acid SCHEMBL30528684 0.87 STAT3 (0.35) STAT3STAT1
SCHEMBL27406238 0.85 STAT3 (0.37) STAT3STAT1
SCHEMBL28269251 0.84 STAT3 (0.37) STAT3STAT1
Hydrogen Sulfide SCHEMBL28226297 0.82 STAT3 (0.36) STAT3STAT1
SCHEMBL28868966 0.82 STAT3 (0.36) STAT3STAT1
SCHEMBL6479855 0.82 STAT3 (0.49) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109652502-A A kind of method and kit of label-free fluorescence detection gene 广东省生态环境技术研究所 2019-04-19 — — CN claimed
CN-105154563-B A method of based on the homogeneous nonstandard detection telomerase activation of triple amplifying techniques 陕西师范大学 2018-10-23 — — CN claimed
CN-107677651-A A kind of Single wavelength excites the Hg that dual signal strengthens2+Ratio fluorescent method 商丘师范学院 2018-02-09 — — CN claimed
CN-107151694-A The Cascaded amplification strategy of ring mediation is used for highly sensitive detection dnmt rna activity 山东大学 2017-09-12 — — CN claimed
CN-101524943-A Method for forming gasochromic pattern on transparent polar plate UNIV ELECTRONIC SCIENCE & TECH 2009-09-09 — — CN claimed
CN-101510014-A Gasochromic device and method for making same UNIV ELECTRONIC SCIENCE & TECH (CN) 2009-08-19 — — CN claimed
CN-1958588-A Synthesis of a kind of compound of new beta - octamethylporphyrin, and application SHANGHAI TEACHER S UNIV (CN) 2007-05-09 — — CN claimed
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-09-28 — — US disclosed
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer ONCOSELECT THERAPEUTICS, LLC (US) 2023-02-28 — — US disclosed
CN-111818944-A Organic silicon dioxide nano-particle with photodynamic activity and medical application thereof 南洋理工大学 2020-10-23 — — CN disclosed
CN-110100829-A Application of the N- methyl porphyrin dipropionic acid IX in Antiphytoviral 华中农业大学 2019-08-09 — — CN disclosed
CN-105154563-B A method of based on the homogeneous nonstandard detection telomerase activation of triple amplifying techniques 陕西师范大学 2018-10-23 — — CN disclosed
EP-1718201-B1 SUBSTITUTED PORPHYRINS UNIV DUKE (US) 2016-09-14 — — EP disclosed
CN-201336637-Y Photoelectric conversion device tracking solar energy automatically CHENGRONG ZHOU (CN) 2009-10-28 — — CN disclosed
CN-101524943-A Method for forming gasochromic pattern on transparent polar plate UNIV ELECTRONIC SCIENCE & TECH 2009-09-09 — — CN disclosed
CN-101510014-A Gasochromic device and method for making same UNIV ELECTRONIC SCIENCE & TECH (CN) 2009-08-19 — — CN disclosed
CN-101225086-A Method for synthesizing mu-oxo binuclear ferriporphyrin UNIV BEIJING TECHNOLOGY (CN) 2008-07-23 — — CN disclosed
US-20080021007-A1 Substituted Porphyrins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-01-24 — — US disclosed
CN-1958588-A Synthesis of a kind of compound of new beta - octamethylporphyrin, and application SHANGHAI TEACHER S UNIV (CN) 2007-05-09 — — CN disclosed
CN-1285832-A Synthesis of long-wavelength absorbing photosensitizers UNIV BRITISH COLUMBIA (CA) 2001-02-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021007-A1 Substituted Porphyrins SOD3, SOD1, PRDX3 STAT3 4525/4885STAT1 4424/4885
US-20230302144-A1 Porphyrin Compounds and Compositions Useful for Treating Cancer KIT, HCCS, PPIF STAT3 1427/4885STAT1 4192/4885
US-11590233-B2 Porphyrin compounds and compositions useful for treating cancer KIT, HCCS, PPIF STAT3 1427/4885STAT1 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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