Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521465 | 0.87 | CHRNA7 (0.46) | CHRNA7HSD17B10LMNAMAPK1ALDH1A1 | |
| SCHEMBL20344283 | 0.78 | ADORA2A (0.42) | LMNACYP1A2TSHRDHODHALDH1A1 | |
| SCHEMBL3526738 | 0.78 | POLB (0.52) | CHRNA7HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL3523491 | 0.78 | CHRNA7 (0.50) | CHRNA7HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL20035085 | 0.77 | ADORA2A (0.51) | LMNAMEN1KMT2ADHODHALDH1A1 | |
| SCHEMBL6329097 | 0.77 | NUDT1 (0.55) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3520562 | 0.75 | CHRNA7 (0.43) | CHRNA7MAPK1KDM4EMAPTNPC1 | |
| SCHEMBL8816383 | 0.75 | TGFBR1 (0.66) | HSD17B10LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6840803 | 0.74 | CLK4 (0.59) | HSD17B10LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3523132 | 0.74 | CHRNA7 (0.46) | CHRNA7HSD17B10LMNACLK4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652006-B2 | For therapy and prophylaxis of neuronal loss associated with stroke, global and focal ischemia, CNS trauma, hypoglycemia and surgery, for ameliorating neurodegenerative diseases | EURO-CELTIQUE S.A. (LU) | 2010-01-26 | — | — | US | disclosed |