SCHEMBL20344283

SCHEMBL20344283

CCc1nc(-c2ccc3ccccc3c2)c2ccccc2n1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
SCN9A Q15858 2/20 0.40
LMNA P02545 1/20 0.40
ADORA1 P30542 1/20 0.40
DHODH Q02127 1/20 0.40
NUDT1 P36639 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40
CCR4 P51679 1/20 0.39
HTR2B P41595 1/20 0.39
HTR5A P47898 1/20 0.39
PRNP P04156 1/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23776019 0.94 ADORA2A (0.43) ADORA2AKDM4EALDH1A1SCN9ALMNA
SCHEMBL20035085 0.84 ADORA2A (0.51) ADORA2AKDM4EALDH1A1LMNADHODH
SCHEMBL6329097 0.84 NUDT1 (0.55) ADORA2AKDM4EALDH1A1LMNANUDT1
SCHEMBL23946289 0.81 CRHR1 (0.43) ADORA2AALDH1A1ADORA1DHODH
SCHEMBL15347069 0.81 SCN9A (0.60) ADORA2ASCN9ADHODH
SCHEMBL29986593 0.80 ADORA2A (0.47) ADORA2AKDM4EALDH1A1LMNAADORA1
SCHEMBL16542821 0.80 ADORA2A (0.47) ADORA2AKDM4EALDH1A1LMNAADORA1
SCHEMBL19169482 0.78 ADORA2A (0.43) ADORA2AKDM4EALDH1A1SCN9AADORA1
SCHEMBL3523482 0.78 CHRNA7 (0.60) ADORA2AKDM4EALDH1A1LMNAADORA1
SCHEMBL17412376 0.78 MEN1 (0.61) ADORA2AKDM4EALDH1A1LMNAADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
EP-3342774-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ADORA2A 139/4885KDM4E 3255/4885ALDH1A1 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.