Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526000 | 0.88 | TSPO (0.52) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL30539311 | 0.75 | TSPO (0.65) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL1170339 | 0.75 | TSPO (0.65) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10985687 | 0.75 | TSPO (0.65) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10987741 | 0.75 | TSPO (0.65) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL15118334 | 0.72 | TSPO (1.00) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL12790424 | 0.72 | TSPO (1.00) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| Pk-11195 SCHEMBL31060347 | 0.72 | TSPO (1.00) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| Pk-11195 SCHEMBL29354252 | 0.72 | TSPO (1.00) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| (R)Pk-11195 SCHEMBL29477174 | 0.72 | TSPO (1.00) | TSPOKMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424532-B1 | COMPOUNDS FOR INDUCING CELLULAR APOPTOSIS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2014-09-24 | — | — | EP | disclosed |
| US-8716302-B2 | Compounds for inducing cellular apoptosis | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2014-05-06 | — | — | US | disclosed |
| US-20120101115-A1 | Compounds For Inducing Cellular Apoptosis | QUEEN MARY AND WESTFIELD COLLEGE (GB) | 2012-04-26 | — | — | US | disclosed |
| WO-2010125343-A1 | COMPOUNDS FOR INDUCING CELLULAR APOPTOSIS | QUEEN MARY AND WESTFIELD COLLEGE (GB) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101115-A1 | Compounds For Inducing Cellular Apoptosis | BAD, BAX, CASP3 | TSPO 1625/4885KMT2A 3252/4885MEN1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.