SCHEMBL352382

SCHEMBL352382

CC(O)C(=O)Oc1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
GAA P10253 4/20 0.44
JAK2 O60674 2/20 0.44
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 4/20 0.44
POLB P06746 1/20 0.44
CA12 O43570 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
ACHE P22303 1/20 0.39
SERPINE1 P05121 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27758659 0.87 ALOX15 (0.48) CA1CA2TP53TSHRGAA
SCHEMBL28575814 0.87 ALOX15 (0.48) CA1CA2TP53TSHRGAA
SCHEMBL10713156 0.86 CA1 (0.48) CA1CA2TP53TSHRGAA
SCHEMBL689262 0.84 GAA (0.47) CA1CA2TP53TSHRGAA
SCHEMBL8399530 0.83 CA1 (0.45) CA1CA2TP53TSHRGAA
SCHEMBL27978203 0.82 CA1 (0.46) CA1CA2TP53TSHRGAA
SCHEMBL1826831 0.81 TDP1 (0.47) KMT2AALDH1A1KDM4EHPGDTDP1
SCHEMBL3361719 0.81 KMT2A (0.53) CA1CA2MAPTLMNAKMT2A
SCHEMBL6371250 0.80 GABRA1 (0.47) CA1CA2TP53TSHRGAA
SCHEMBL10787248 0.80 GAA (0.44) CA1CA2TP53TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210069268-A1 METABOLOMIC REVISION OF MAMMALIAN INFANTS Evolve Biosystems, Inc. (US) 2021-03-11 US claimed
CN-111587376-A Metabonomics modification of mammalian infants 进化生物系统股份有限公司 2020-08-25 CN claimed
EP-3681521-A1 METABOLOMIC REVISION OF MAMMALIAN INFANTS Evolve Biosystems Inc. (US) 2020-07-22 EP claimed
WO-2019055718-A1 METABOLOMIC REVISION OF MAMMALIAN INFANTS Evolve Biosystems, Inc. (US) 2019-03-21 WO claimed
US-5834510-A TOPICAL APPLICATION TRISTRATA TECHNOLOGY, INC. 1998-11-10 US claimed
CN-117342953-A Use of rosmarinic acid and analogues thereof in the treatment of vascular diseases 西北大学 2024-01-05 CN disclosed
CN-117304022-A Method for synthesizing rosmarinic acid and analogues thereof 西北大学 2023-12-29 CN disclosed
CN-114746745-A Detection of analytes by protein switches 美国雅培糖尿病护理公司 2022-07-12 CN disclosed
US-20210069268-A1 METABOLOMIC REVISION OF MAMMALIAN INFANTS Evolve Biosystems, Inc. (US) 2021-03-11 US disclosed
CN-111989042-A Lactate sensor and related methods 雅培糖尿病护理股份有限公司 2020-11-24 CN disclosed
US-10842728-B2 Light-absorbing compositions and methods of use ALLELE BIOTECHNOLOGY & PHARMACEUTICALS, INC. (US) 2020-11-24 US disclosed
CN-111587376-A Metabonomics modification of mammalian infants 进化生物系统股份有限公司 2020-08-25 CN disclosed
EP-1012164-A1 SERINE PROTEASE INHIBITORS Akzo Nobel N.V. (NL) 2000-06-28 EP disclosed
WO-1997031939-A1 SERINE PROTEASE INHIBITORS AKZO NOBEL N.V. (NL) 1997-09-04 WO disclosed
CN-1028098-C Preparation of amino ketone compound MONSANTO CO (US) 1995-04-05 CN disclosed
EP-0413528-A1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1991-02-20 EP disclosed
CN-1049338-A The preparation method of amino ketone compound PHARMACEUTICALS INST CHINESE A (CN) 1991-02-20 CN disclosed
EP-0052927-B1 STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-01-07 EP disclosed
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10842728-B2 Light-absorbing compositions and methods of use CYBA, BROX, S100A6 CA1 2077/4885CA2 2873/4885TP53 2408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.