Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524033 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10132433 | 0.97 | ALDH1A1 (0.50) | ALDH1A1NPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10132456 | 0.88 | NPC1 (0.52) | ALDH1A1NPC1LMNANPSR1UCHL1 | |
| SCHEMBL3532143 | 0.82 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2CACNA1GCACNA1H | |
| SCHEMBL3532138 | 0.82 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2CACNA1GCACNA1H | |
| SCHEMBL10132381 | 0.80 | ALDH1A1 (0.54) | ALDH1A1NPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10132254 | 0.80 | UCHL1 (0.53) | ALDH1A1NPC1LMNANPSR1UCHL1 | |
| SCHEMBL10132357 | 0.80 | ALDH1A1 (0.56) | ALDH1A1NPC1LMNANPSR1UCHL1 | |
| SCHEMBL10132339 | 0.79 | NPC1 (0.56) | ALDH1A1NPC1LMNANPSR1UCHL1 | |
| SCHEMBL1429462 | 0.79 | NPC1 (0.58) | ALDH1A1NPC1LMNANPSR1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298377-A1 | NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298377-A1 | NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF AND USE OF SAME IN THERAPEUTICS | WEE1, PRMT1, ABL1 | ALDH1A1 118/4885NPC1 367/4885TAS1R3 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.