Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286537 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMAOBLMNATRPA1 | |
| SCHEMBL27930015 | 0.83 | TRPA1 (0.40) | ALDH1A1TSHRMAOBLMNATRPA1 | |
| SCHEMBL5599476 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNABTN3A1FFAR1 | |
| SCHEMBL5599478 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNABTN3A1FFAR1 | |
| SCHEMBL13589779 | 0.79 | MAOB (0.44) | ALDH1A1TSHRMAOBLMNATRPA1 | |
| SCHEMBL26306910 | 0.79 | MAOB (0.44) | ALDH1A1TSHRMAOBLMNATRPA1 | |
| SCHEMBL5814465 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27957287 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL96315 | 0.78 | MAOB (0.48) | ALDH1A1TSHRMAOBLMNATRPA1 | |
| SCHEMBL96316 | 0.78 | MAOB (0.48) | ALDH1A1TSHRMAOBLMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710264-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2014-04-29 | — | — | US | disclosed |
| US-8710264-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2014-04-29 | — | — | US | disclosed |
| EP-2231590-B9 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2012-08-15 | — | — | EP | disclosed |
| EP-2231590-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2012-03-14 | — | — | EP | disclosed |
| US-20120041063-A2 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2012-02-16 | — | — | US | disclosed |
| US-20120041063-A2 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2012-02-16 | — | — | US | disclosed |
| US-20100280108-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2010-11-04 | — | — | US | disclosed |
| US-20100280108-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2010-11-04 | — | — | US | disclosed |
| WO-2009080769-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041063-A2 | ANTITUMORAL COMPOUNDS | TPD52L2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TP53 | ALDH1A1 1599/4885TSHR 613/4885MAOB 3216/4885 |
| US-20100280108-A1 | Antitumoral Compounds | TPD52L2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TP53 | ALDH1A1 1599/4885TSHR 613/4885MAOB 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.