Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 17/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154693 | 0.81 | MAPT (0.46) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL27603459 | 0.81 | THRB (0.48) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL5731610 | 0.81 | P2RX4 (0.42) | ALDH1A1MAPTITGA4 | |
| SCHEMBL987799 | 0.79 | THRB (0.55) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL996855 | 0.75 | THRB (0.43) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL996856 | 0.74 | THRB (0.42) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL29663083 | 0.73 | THRB (0.59) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL3245527 | 0.73 | THRB (0.59) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL16137604 | 0.73 | THRB (0.44) | ALDH1A1MAPTITGA4THRBTDP1 | |
| SCHEMBL18894103 | 0.72 | MAPT (0.38) | ALDH1A1MAPTITGA4THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10688522-B2 | Method of coating a lens and lens support | TRANSITIONS OPTICAL, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-10619098-B2 | Ultraviolet light absorbers | TRANSITIONS OPTICAL, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-10444537-B2 | Optical article having a photoluminescent mark | TRANSITIONS OPTICAL, INC. (US) | 2019-10-15 | — | — | US | disclosed |
| US-10281628-B2 | Method of preparing a photochromic optical article using an organic solvent pretreatment and photochromic coating | TRANSITIONS OPTICAL, INC. (US) | 2019-05-07 | — | — | US | disclosed |
| EP-3248054-B1 | OPTICAL ARTICLE HAVING A PHOTOLUMINESCENT MARK | TRANSITIONS OPTICAL INC (US) | 2018-12-12 | — | — | EP | disclosed |
| EP-3201292-B1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL INC (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-3071401-B9 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL INC (US) | 2018-03-14 | — | — | EP | disclosed |
| US-20180024377-A1 | Optical Article Having a Photoluminescent Mark | TRANSITIONS OPTICAL, INC. | 2018-01-25 | — | — | US | disclosed |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-3071401-B1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-1196466-B1 | POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) | PPG IND OHIO INC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1497288-A1 | NOVEL ESTER HYDROXY-SUBSTITUTED NITROGEN HETEROCYCLES AS ANTAGONISTS OF THE MUSCARINIC M3 RECEPTOR, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-01-19 | — | — | EP | disclosed |
| EP-1494680-A1 | USE OF CARBON-2-MODIFIED-VITAMIN D ANALOGS TO INDUCE THE FORMATION OF NEW BONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-1472251-A1 | NOVEL FLUORENE CARBOXYLIC ACID ESTERS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS PHARMACEUTICALS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003087096-A1 | NOVEL ESTER HYDROXY-SUBSTITUTED NITROGEN HETEROCYCLES AS ANTAGONISTS OF THE MUSCARINIC M3 RECEPTOR, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-10-23 | — | — | WO | disclosed |
| WO-2003082300-A1 | USE OF CARBON-2-MODIFIED-VITAMIN D ANALOGS TO INDUCE THE FORMATION OF NEW BONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-10-09 | — | — | WO | disclosed |
| WO-2003064419-A1 | NOVEL FLUORENE CARBOXYLIC ACID ESTERS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS PHARMACEUTICALS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-08-07 | — | — | WO | disclosed |
| EP-1268416-A1 | 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS AND THEIR THERAPEUTIC USES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6316570-B1 | FOR PRODUCING POLYMERIZATES HAVING CLARITY, GOOD FLEXIBILITY, ABRASION RESISTANCE WHICH ARE USED IN PREPARATION OF MOLDED ARTICLES SUCH AS LENSES | PPG INDUSTRIES OHIO, INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2001074766-A1 | 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS AND THEIR THERAPEUTIC USES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619098-B2 | Ultraviolet light absorbers | ERCC1, MCM4, ERCC4 | ALDH1A1 590/4885MAPT 80/4885ITGA4 2332/4885 |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | MCM4, ERCC1, ERCC4 | ALDH1A1 392/4885MAPT 85/4885ITGA4 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.