SCHEMBL16137604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19886297	0.84	PDK2 (0.38)	PDK2
	SCHEMBL16137603	0.84	THRB (0.41)	THRBTDP1PDK2APEX1ALDH1A1
	SCHEMBL987799	0.77	THRB (0.55)	THRBTDP1PDK2APEX1ALDH1A1
	SCHEMBL27603459	0.76	THRB (0.48)	THRBTDP1PDK2APEX1ALDH1A1
	SCHEMBL1072634	0.74	THRB (0.46)	THRBTDP1APEX1ALDH1A1MAPT
	SCHEMBL996855	0.74	THRB (0.43)	THRBTDP1PDK2APEX1ALDH1A1
	SCHEMBL9610527	0.73	GRK6 (0.35)	THRBALDH1A1MAPTKMT2ATYMS
	SCHEMBL3524770	0.73	ALDH1A1 (0.46)	THRBTDP1PDK2ALDH1A1MAPT
	SCHEMBL996856	0.72	THRB (0.42)	THRBTDP1PDK2APEX1ALDH1A1
	SCHEMBL17050289	0.70	KMT2A (0.46)	THRBTDP1PDK2APEX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.