Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524770 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL3633870 | 0.81 | THRB (0.48) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL5731715 | 0.81 | P2RX4 (0.42) | MAPTALDH1A1ITGA4KMT2ALMNA | |
| SCHEMBL19335310 | 0.76 | THRB (0.40) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL2774493 | 0.75 | ELANE (0.41) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL15108313 | 0.73 | MAPT (0.43) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL4217613 | 0.73 | ALDH1A1 (0.49) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL21136952 | 0.72 | SLC25A5 (0.35) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL18894103 | 0.72 | MAPT (0.38) | MAPTALDH1A1ITGA4TDP1THRB | |
| SCHEMBL13126124 | 0.71 | ALDH1A1 (0.38) | MAPTALDH1A1ITGA4TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472250-B1 | ANTICHOLINERGIC AGENTS, METHOD FOR PRODUCING THE SAME AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2014-11-26 | — | — | EP | disclosed |
| EP-1561751-A1 | Fluorene carboxylic acid esters, methods for the production thereof, and use of the same as pharmaceuticals | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-08-10 | — | — | EP | disclosed |
| EP-1472251-B1 | NOVEL FLUORENE CARBOXYLIC ACID ESTERS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS PHARMACEUTICALS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1472251-A1 | NOVEL FLUORENE CARBOXYLIC ACID ESTERS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS PHARMACEUTICALS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-11-03 | — | — | EP | disclosed |
| EP-1472250-A1 | ANTICHOLINERGIC AGENTS, METHOD FOR PRODUCING THE SAME AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064418-A1 | ANTICHOLINERGIC AGENTS, METHOD FOR PRODUCING THE SAME AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003064419-A1 | NOVEL FLUORENE CARBOXYLIC ACID ESTERS, METHODS FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS PHARMACEUTICALS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-08-07 | — | — | WO | disclosed |