Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | PPARD | Q03181 | 11/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524932 | 0.90 | PPARG (0.50) | PPARGPPARAPPARDACLYPHGDH | |
| SCHEMBL3522637 | 0.90 | PPARG (0.69) | PPARGPPARAPPARDACLY | |
| SCHEMBL3527397 | 0.88 | PPARG (0.67) | PPARGPPARAPPARDACLY | |
| SCHEMBL3520953 | 0.88 | PPARG (0.54) | PPARGPPARAPPARDPHGDH | |
| SCHEMBL3524916 | 0.86 | PPARG (0.56) | PPARGPPARAPPARDACLY | |
| SCHEMBL3533511 | 0.85 | NOD1 (0.41) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL3526453 | 0.82 | PPARG (0.66) | PPARGPPARAPPARDACLY | |
| SCHEMBL3528077 | 0.82 | PPARG (0.59) | PPARGPPARAPPARDACLY | |
| SCHEMBL3529263 | 0.81 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL3524214 | 0.80 | PPARG (0.52) | PPARGPPARAPPARDACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436040-B2 | Method of treating conditions involving PPAR-receptors with indole compounds | LABORATOIRES FOURNIER S.A. (FR) | 2013-05-07 | — | — | US | disclosed |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | LABORATORIES FOURNIER S.A. (FR) | 2010-11-11 | — | — | US | disclosed |
| US-7795297-B2 | Indole compounds, method of preparing them and uses thereof | LABORATORIES FOURNIER S.A. (FR) | 2010-09-14 | — | — | US | disclosed |
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LABORATOIRES FOURNIER S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LIPG, GPR119, IAPP | PPARG 1018/4885PPARA 847/4885PPARD 677/4885 |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | GPR119, PPARA, PPARG | PPARG 3/4885PPARA 2/4885PPARD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.