Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629872 | 0.88 | GRM5 (0.46) | L3MBTL1HTTRECQLALDH1A1GAA | |
| SCHEMBL11631991 | 0.87 | L3MBTL1 (0.51) | L3MBTL1HTTRECQLALDH1A1GAA | |
| SCHEMBL5655555 | 0.83 | L3MBTL1 (0.51) | L3MBTL1HTTRECQLALDH1A1GAA | |
| SCHEMBL11814736 | 0.77 | HTT (0.39) | L3MBTL1HTTRECQLCCR1CCR8 | |
| SCHEMBL11821663 | 0.76 | RECQL (0.38) | L3MBTL1HTTRECQLCCR1CCR8 | |
| SCHEMBL954513 | 0.75 | CCR1 (0.52) | HTTRECQLCCR1CCR8NOS3 | |
| SCHEMBL16545967 | 0.74 | HTT (0.37) | L3MBTL1HTTRECQLCCR1CCR8 | |
| SCHEMBL102150 | 0.73 | CCR1 (0.50) | HTTRECQLCCR1CCR8NOS3 | |
| Acetonitrile SCHEMBL1327931 | 0.72 | CCR1 (0.55) | CCR1CCR8NOS3NOS2ALDH1A1 | |
| SCHEMBL21240439 | 0.72 | HTT (0.38) | HTTRECQLCCR1CCR8NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709533-B2 | Imines as ion channel modulators | ICAGEN, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-1861356-A1 | IMINES AS ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| US-20060178346-A1 | Imines as ion channel modulators | ICAGEN, INC. (US) | 2006-08-10 | — | — | US | disclosed |
| WO-2006084031-A1 | IMINES AS ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178346-A1 | Imines as ion channel modulators | KCNN1, KCNN3, KCNN2 | L3MBTL1 3514/4885HTT 322/4885RECQL 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.