SCHEMBL3525962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3724533	0.83	MAP4K4 (0.46)	PRKD3MAP4K4MAPK9CSNK1A1CSNK1D
	SCHEMBL3524359	0.83	NPC1 (0.47)	PRKD3MAP4K4MAPK9CSNK1A1CSNK1D
	SCHEMBL3523202	0.77	KMO (0.40)	ADORA2AADORA1TGFBR1KMOF2RL3
	SCHEMBL3242198	0.77	MAPK9 (0.42)	PRKD3MAP4K4MAPK9CSNK1A1CSNK1D
	SCHEMBL13368329	0.73	KMO (0.51)	MAPK9CSNK1A1CSNK1DMAPK8GSK3B
	SCHEMBL3663945	0.70	MAPK9 (0.68)	PRKD3MAP4K4MAPK9CSNK1A1CSNK1D
	SCHEMBL3528770	0.70	ALPL (0.47)	KMOF2RL3PDE3BPDE3A
	SCHEMBL3524337	0.69	MAPK9 (0.66)	PRKD3MAP4K4MAPK9CSNK1A1CSNK1D
	SCHEMBL3527167	0.66	PDE3B (0.49)	DYRK1AADORA2AADORA1TGFBR1KMO
	SCHEMBL3529079	0.65	NPC1 (0.51)	METADORA2AADORA1TGFBR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.