SCHEMBL3526784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11289039	0.86	TAAR1 (0.51)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL6299555	0.86	CYP2D6 (0.58)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL3530042	0.85	TAAR1 (0.50)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL3529776	0.84	TAAR1 (0.46)	TAAR1F2RL1HTR1A
	SCHEMBL11299695	0.80	TAAR1 (0.50)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL3530217	0.78	TAAR1 (0.39)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL3527671	0.77	TAAR1 (0.55)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4
	SCHEMBL11293853	0.76	TAAR1 (0.55)	TAAR1F2RL1HTR1AADRA2AADRA2C
	SCHEMBL11566236	0.75	ADRA2A (0.54)	TAAR1CYP1A2CYP2C19CYP3A4CYP2D6
	SCHEMBL7518159	0.75	ADRA2C (0.46)	TAAR1F2RL1CYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.