SCHEMBL352782

SCHEMBL352782

C=C(COC)C(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353002 0.84 ALDH1A1 (0.48)
SCHEMBL20261881 0.81 ALDH1A1 (0.41)
SCHEMBL16520256 0.80
SCHEMBL21422347 0.80
SCHEMBL351718 0.78 ALDH1A1 (0.48)
SCHEMBL351841 0.78 ALDH1A1 (0.42)
SCHEMBL4513312 0.78 ALDH1A1 (0.47)
SCHEMBL11603931 0.78 ALDH1A1 (0.52)
SCHEMBL11597745 0.78 ALDH1A1 (0.33)
SCHEMBL31712055 0.77 DGAT1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020120143-A1 Process for the preparation of 2,3-pyridinedicarboximides INTELLECTUAL PROPERTY DEPARTMENT, BASF AKTIENGESELLSCHAFT (DE) 2002-08-29 US claimed
US-12624051-B2 Macrocyclic compounds, compositions, and methods of using thereof GENZYME CORPORATION (US) 2026-05-12 US disclosed
US-20260102383-A1 LPAR1 Inhibitors ABBVIE INC (US) 2026-04-16 US disclosed
US-20260008786-A1 MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SCHRODINGER, LLC 2026-01-08 US disclosed
US-20260008785-A1 MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SCHRODINGER, LLC 2026-01-08 US disclosed
WO-2025226510-A1 LPAR1 INHIBITORS ABBVIE INC. (US) 2025-10-30 WO disclosed
EP-4640274-A1 LPAR1 INHIBITORS AbbVie Inc. (US) 2025-10-29 EP disclosed
US-12454622-B2 Coating providing controlled absorption and scattering EASTMAN KODAK COMPANY (US) 2025-10-28 US disclosed
US-12428566-B2 Coating providing panchromatic scattering EASTMAN KODAK COMPANY (US) 2025-09-30 US disclosed
EP-4583972-A1 MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF Sionna Therapeutics Inc. (US) 2025-07-16 EP disclosed
EP-1984331-A1 PYRROLIDINE DERIVATIVES AS ERK INHIBITORS SCHERING CORPORATION (US) 2008-10-29 EP disclosed
EP-1966151-A1 POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS SCHERING CORPORATION (US) 2008-09-10 EP disclosed
US-20070232610-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-10-04 US disclosed
WO-2007097937-A1 PYRROLIDINE DERIVATIVES AS ERK INHIBITORS SCHERING CORPORATION (US) 2007-08-30 WO disclosed
WO-2007097937-A1 PYRROLIDINE DERIVATIVES AS ERK INHIBITORS SCHERING CORPORATION (US) 2007-08-30 WO disclosed
US-20070191604-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-08-16 US disclosed
WO-2007070398-A1 POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS SCHERING CORPORATION (US) 2007-06-21 WO disclosed
WO-2007070398-A1 POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS SCHERING CORPORATION (US) 2007-06-21 WO disclosed
CN-1043242-C Treating composition of metallic surface having excellent lubricity NIHON PARKERIZING (JP) 1999-05-05 CN disclosed
CN-1053638-A Metal surface treating composition with good oilness NIPON PARKERIZING CO LTD (JP) 1991-08-07 CN disclosed