Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524833 | 0.90 | SLC22A2 (0.51) | SLC22A2 | |
| SCHEMBL3529763 | 0.89 | SLC22A2 (0.43) | SLC22A2 | |
| SCHEMBL3525528 | 0.87 | MAPK1 (0.50) | — | |
| SCHEMBL2187373 | 0.85 | SLC22A2 (0.43) | SLC22A2 | |
| SCHEMBL2185556 | 0.85 | — | — | |
| SCHEMBL2186099 | 0.85 | TP53 (0.43) | — | |
| SCHEMBL3524286 | 0.85 | ELANE (0.42) | SLC22A2 | |
| SCHEMBL2185146 | 0.85 | P2RX7 (0.47) | P2RX7SLC22A2 | |
| SCHEMBL2187307 | 0.84 | P2RX7 (0.50) | P2RX7KLKB1 | |
| SCHEMBL2186850 | 0.84 | ELANE (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858788-B2 | Bicyclic carbamoylpyridone derivative having HIV integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| EP-1852434-A1 | BICYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITING ACTIVITY | Shionogi Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |