Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186878 | 0.92 | MEN1 (0.39) | SLC22A2 | |
| SCHEMBL3523992 | 0.91 | SLC22A2 (0.47) | SLC22A2 | |
| SCHEMBL2186850 | 0.90 | ELANE (0.45) | ELANE | |
| SCHEMBL2186243 | 0.90 | PDE2A (0.43) | SLC22A2 | |
| SCHEMBL2186951 | 0.90 | SLC22A2 (0.41) | SLC22A2 | |
| SCHEMBL3528016 | 0.89 | ALDH1A1 (0.43) | — | |
| SCHEMBL2185146 | 0.88 | P2RX7 (0.47) | SLC22A2 | |
| SCHEMBL3529420 | 0.86 | SLC22A2 (0.46) | SLC22A2 | |
| SCHEMBL2186862 | 0.85 | SLC22A2 (0.46) | SLC22A2 | |
| SCHEMBL3528388 | 0.85 | P2RX7 (0.50) | SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858788-B2 | Bicyclic carbamoylpyridone derivative having HIV integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| EP-1852434-A1 | BICYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITING ACTIVITY | Shionogi Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |