Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FECH | P22830 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353038 | 1.00 | HTR2A (0.41) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL351289 | 1.00 | HTR2A (0.41) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL352366 | 1.00 | HTR2A (0.41) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL15444487 | 0.87 | HTR2A (0.40) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL351295 | 0.84 | HTR2A (0.44) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL352320 | 0.84 | HTR2A (0.44) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL31268264 | 0.81 | ADRA2C (0.46) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL13003640 | 0.81 | SLC6A4 (0.46) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL31373415 | 0.81 | ADRA2C (0.46) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 | |
| SCHEMBL27906798 | 0.81 | ADRA2C (0.46) | HTR2ASLC6A4SLC6A2HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648190-B2 | Process for producing 2-hydroxymethylmorpholine salt | DAISO CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2388252-B1 | PROCESS FOR PRODUCING 2-HYDROXYMETHYLMORPHOLINE SALT | DAISO CO LTD (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20120016120-A1 | PROCESS FOR PRODUCING 2-HYDROXYMETHYLMORPHOLINE SALT | DAISO CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| EP-2388252-A1 | PROCESS FOR PRODUCING 2-HYDROXYMETHYLMORPHOLINE SALT | Daiso Co., Ltd. (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-8040010-B2 | Permanent magnet type generator and hybrid vehicle using the same | HITACHI, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016120-A1 | PROCESS FOR PRODUCING 2-HYDROXYMETHYLMORPHOLINE SALT | THOP1, AVPR2, HPD | HTR2A 16/4885SLC6A4 111/4885SLC6A2 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.