Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958926 | 0.90 | TYMP (0.33) | TYMPPDE3BPDE3A | |
| SCHEMBL28555095 | 0.89 | — | — | |
| SCHEMBL1086664 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL5077 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL37842 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL467389 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL467388 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL1086667 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL5078 | 0.89 | ELANE (0.34) | TYMP | |
| SCHEMBL10564949 | 0.89 | ELANE (0.34) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820838-B2 | Method for total synthesis of ecteinascidins and intermediate compounds thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7807833-B2 | Method for total synthesis of ecteinascidins and intermediate compounds thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20090198051-A1 | Method For Total Synthesis Of Ecteinascidins And Intermediate Compounds Thereof | FUKUYAMA TOHRU | 2009-08-06 | — | — | US | disclosed |
| US-20090036673-A1 | Method For Total Synthesis Of Ecteinascidins And Intermediate Compounds Thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-02-05 | — | — | US | disclosed |
| US-7417145-B2 | Process for total synthesis of ecteinascidins and intermediates therefor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-08-26 | — | — | US | disclosed |
| EP-1812381-A1 | ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006049264-A1 | ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE | SHOWA DENKO K.K. (JP) | 2006-05-11 | — | — | WO | disclosed |
| US-20050043308-A1 | Process for total synthesis of ecteinascidins and intermediates therefor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1471068-A1 | PROCESS FOR TOTAL SYNTHESIS OF ECTEINASCIDINS AND INTERMEDIATES THEREFOR | Japan Science and Technology Agency (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-1317691-A2 | PHOTOSENSITIVE COMPOSITION, CURED ARTICLE THEREOF, AND PRINTED CIRCUIT BOARD USING THE SAME | Showa Denko K.K. (JP) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002023273-A2 | PHOTOSENSITIVE COMPOSITION, CURED ARTICLE THEREOF, AND PRINTED CIRCUIT BOARD USING THE SAME | SHOWA DENKO K.K. (JP) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043308-A1 | Process for total synthesis of ecteinascidins and intermediates therefor | TKFC, CYP4F2, ERLIN2 | TYMP 373/4885PDE3B 4510/4885PDE3A 4598/4885 |
| US-20090036673-A1 | Method For Total Synthesis Of Ecteinascidins And Intermediate Compounds Thereof | ERLIN2, ETF1, TXN2 | TYMP 356/4885PDE3B 3967/4885PDE3A 4140/4885 |
| US-20090198051-A1 | Method For Total Synthesis Of Ecteinascidins And Intermediate Compounds Thereof | ERLIN2, ETF1, TXN2 | TYMP 356/4885PDE3B 3967/4885PDE3A 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.