Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534125 | 0.83 | CARM1 (0.44) | CARM1PRMT6KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3288118 | 0.82 | SMN1; SMN2 (0.40) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3294393 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3288471 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3293459 | 0.78 | LMNA (0.47) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3288540 | 0.75 | POLB (0.46) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3287069 | 0.75 | ALDH1A1 (0.42) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3530286 | 0.72 | ALDH1A1 (0.47) | CARM1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL3291165 | 0.71 | P2RX7 (0.44) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3535326 | 0.71 | P2RX7 (0.48) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | disclosed |