Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352115 | 0.89 | CNR2 (0.36) | CNR2ALDH1A1GAAKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL353958 | 0.85 | KCNH2 (0.45) | CNR2ALDH1A1GAAKCNH2 | |
| Iodide SCHEMBL352068 | 0.84 | KDM4E (0.37) | CNR2LMNACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16494730 | 0.82 | CNR2 (0.39) | CNR2MCHR1ALDH1A1GAATERT | |
| SCHEMBL354256 | 0.82 | INSR (0.33) | CNR2LMNACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL354255 | 0.81 | INSR (0.34) | CNR2LMNACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10341022 | 0.77 | APP (0.38) | CNR2MCHR1ALDH1A1GAATERT | |
| SCHEMBL10340943 | 0.77 | APP (0.38) | CNR2MCHR1ALDH1A1GAATERT | |
| SCHEMBL10031417 | 0.74 | INSR (0.38) | CNR2 | |
| SCHEMBL27994253 | 0.71 | KCNH2 (0.58) | CNR2MCHR1ALDH1A1GAATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015399-A1 | FLUORESCENT SOLVATOCHROMIC PIGMENT | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2012-01-19 | — | — | US | disclosed |
| EP-2395055-A1 | FLUORESCENT SOLVATOCHROMIC PIGMENT | National University Corporation Hokkaido University (JP) | 2011-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015399-A1 | FLUORESCENT SOLVATOCHROMIC PIGMENT | ANXA5, TRPV5, TRPC5 | CNR2 2082/4885MCHR1 252/4885ALDH1A1 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.