SCHEMBL353233

SCHEMBL353233

O=C(O)CC1C2CC(C1C(=O)O)C(C(=O)O)C2C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.43
▸ POLB P06746 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ SLC6A12 P48065 3/20 0.37
▸ SLC6A11 P48066 3/20 0.37
▸ SLC6A13 Q9NSD5 3/20 0.37
▸ SLC1A2 P43004 4/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ THPO P40225 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ GRIK1 P39086 1/20 0.33
▸ GRM5 P41594 1/20 0.33
▸ GRIA1 P42261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16249890 0.89 HSD11B1 (0.42) HSD11B1POLBTDP1SLC6A12SLC6A11
SCHEMBL16249613 0.82 HSD11B1 (0.39) HSD11B1POLBTDP1SLC6A12SLC6A11
SCHEMBL4336511 0.82 POLB (0.36) POLBTDP1MAPK1
SCHEMBL18912876 0.79 HSD11B1 (0.37) HSD11B1POLBTDP1SLC6A12SLC6A11
SCHEMBL432536 0.78 POLB (0.57) POLBTDP1SLC1A2MEN1KMT2A
SCHEMBL13346677 0.77 POLB (0.41) HSD11B1POLBTDP1ALDH1A1LMNA
SCHEMBL4336521 0.76 LMNA (0.33) POLBTDP1LMNA
SCHEMBL16522346 0.76 HSD11B1 (0.35) HSD11B1POLBTDP1
SCHEMBL7857014 0.75 HSD11B1 (0.34) HSD11B1POLBTDP1LMNA
SCHEMBL16351613 0.74 HSD11B1 (0.33) HSD11B1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989433-A Resin, positive photosensitive resin composition and application 烟台三月科技有限责任公司 2022-09-02 — — CN claimed
CN-114524938-A Polymer, photosensitive resin composition, cured film prepared from same and electronic element 江苏三月科技股份有限公司 2022-05-24 — — CN claimed
CN-113677741-A Bismaleimide compound, photosensitive resin composition using the same, cured product thereof, and semiconductor device 日本化药株式会社 2021-11-19 — — CN claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 — — EP claimed
US-9133353-B2 Low temperature curable polyimide resin and method of preparing the same LG CHEM, LTD. (KR) 2015-09-15 — — US claimed
US-20120016076-A1 LOW TEMPERATURE CURABLE POLYIMIDE RESIN AND METHOD OF PREPARING THE SAME LG CHEM. LTD. (KR) 2012-01-19 — — US claimed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 — — US claimed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 — — EP claimed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 — — US claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 — — US claimed
US-7034098-B2 POlyimide, polyamide; liquid crystals, opticsoptics ROLIC AG (CH) 2006-04-25 — — US claimed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 — — US claimed
EP-1368411-B1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2005-07-06 — — EP claimed
US-20040185215-A1 Photoactive polymer based on polyimides, polyamic acids and esters characterised in that it contains as a side-chain a dendritic block incorporating photoactive groups at its surface; use as orientation layers for liquid crystals and in the construction of unstructured and structured optical elements ROLIC AG (CH) 2004-09-23 — — US claimed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 — — EP claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 — — EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 — — WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 — — WO claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 — — EP claimed
US-5637359-A POLYIMIDE ALIGNING FILM IS FORMED BY DISSOLVING HIGH TEMPERATURE SINTERING POLYIMIDE IN SOLVENT, PRINTING RESULTING SOLUTION IN A SUBSTRATE AND REMOVING SOLVENT BY HEATING OR HEATING UNDER REDUCED PRESSURE SHARP KABUSHIKI KAISHA (JP) 1997-06-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO HSD11B1 4481/4885POLB 1573/4885TDP1 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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