Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663258 | 0.89 | LMNA (0.40) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL3587106 | 0.82 | MAPT (0.46) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL3595140 | 0.81 | MAPT (0.48) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL27563569 | 0.79 | SMN1; SMN2 (0.47) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL6642153 | 0.79 | MAPT (0.46) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL4061267 | 0.79 | MAPT (0.52) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL9370451 | 0.79 | MAPT (0.49) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL353361 | 0.78 | KDM4E (0.59) | MAPTLMNAALDH1A1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL9753901 | 0.78 | SMN1; SMN2 (0.46) | MAPTTBXAS1LMNAMAPK1PKM | |
| SCHEMBL29852705 | 0.78 | MAPT (0.64) | MAPTTBXAS1LMNAMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196889-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS | CANAM BIORESEARCH INC. (CA) | 2015-07-16 | — | — | US | disclosed |
| US-8926801-B2 | Methods of electrospray chemical synthesis and device for use therein | CANAM BIORESEARCH INC. (CA) | 2015-01-06 | — | — | US | disclosed |
| US-20120012453-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS AND DEVICE FOR USE THEREIN | CANAM BIORESEARCH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| WO-2010081236-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS AND DEVICE FOR USE THEREIN | CANAM BIORESEARCH INC. (CA) | 2010-07-22 | — | — | WO | disclosed |