SCHEMBL3532550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3534571	0.96	LMNA (0.55)	LMNAHPGDMCL1MEN1KMT2A
	SCHEMBL14278777	0.90	MEN1 (0.65)	LMNAHPGDMCL1MEN1KMT2A
	SCHEMBL9658088	0.88	MEN1 (0.63)	LMNAHPGDMCL1MEN1KMT2A
	SCHEMBL8122663	0.87	RXRA (0.56)	LMNAHPGDMEN1KMT2ANR4A2
	SCHEMBL1053465	0.86	SMN1; SMN2 (0.49)	LMNAHPGDMCL1MEN1KMT2A
	SCHEMBL3535264	0.86	LMNA (0.52)	LMNAHPGDMCL1MEN1KMT2A
	SCHEMBL9370136	0.83	MCL1 (0.52)	LMNAHPGDMCL1P4HTMALDH1A1
	SCHEMBL20510001	0.82	LMNA (0.52)	LMNAHPGDMEN1KMT2AP4HTM
	SCHEMBL112672	0.82	MEN1 (0.59)	LMNAMEN1KMT2AALDH1A1MAOB
	SCHEMBL9658085	0.82	MCL1 (0.55)	HPGDMCL1MEN1KMT2AP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.