Sugi Predict

Sugi Predict / Compounds / SCHEMBL353299

SCHEMBL353299

SCHEMBL353299

CCCCCc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.64
▸ HSD17B10 Q99714 3/20 0.62
▸ KDM4E B2RXH2 3/20 0.62
▸ ALDH1A1 P00352 3/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ MAPT P10636 2/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ USP2 O75604 1/20 0.62
▸ GAA P10253 1/20 0.62
▸ HPGD P15428 1/20 0.62
▸ SMN1; SMN2 Q16637 1/20 0.62
▸ RARB P10826 6/20 0.58
▸ TSHR P16473 1/20 0.58
▸ MAOB P27338 2/20 0.57
▸ RARA P10276 1/20 0.56
▸ MTOR P42345 1/20 0.56
▸ ESR1 P03372 2/20 0.53
▸ ADRA2A P08913 2/20 0.53
▸ ADORA3 P0DMS8 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12293773 1.00 HTR2A (0.64) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL10905830 0.98 HTR2A (0.68) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL3700777 0.98 HTR2A (0.68) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL1312482 0.98 HTR2A (0.68) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL15198798 0.94 RARB (0.56) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL109256 0.94 HTR2A (0.72) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL23754742 0.91 HTR2A (0.76) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL22346199 0.91 HTR2A (0.76) HTR2AHSD17B10KDM4EALDH1A1RAB9A
Tridecane SCHEMBL22346186 0.91 HTR2A (0.76) HTR2AHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL23754735 0.91 HTR2A (0.76) HTR2AHSD17B10KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-10199577-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2019-02-05 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
EP-2217674-B1 ELECTROACTIVE MATERIALS DU PONT (US) 2017-08-23 — — EP disclosed
EP-2217674-B1 ELECTROACTIVE MATERIALS DU PONT (US) 2017-08-23 — — EP disclosed
US-20170040539-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2017-02-09 — — US disclosed
US-20170040539-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2017-02-09 — — US disclosed
US-9515267-B2 Electroactive materials EI DU PONT DE NEMOURS AND COMPANY (US) 2016-12-06 — — US disclosed
US-8063399-B2 Electroactive materials E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-22 — — US disclosed
US-20110095269-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2011-04-28 — — US disclosed
US-20110095269-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2011-04-28 — — US disclosed
US-20110095269-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY 2011-04-28 — — US disclosed
EP-2217674-A1 ELECTROACTIVE MATERIALS E. I. du Pont de Nemours and Company (US) 2010-08-18 — — EP disclosed
US-7678545-B2 Polyelectrolyte multilayer films at liquid-liquid interfaces and methods for providing and using same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-03-16 — — US disclosed
EP-2108691-A1 Structured films with a controlled tilted molecular orientation and shape using a dichroic photoinitiator. Stichting Dutch Polymer Institute (NL) 2009-10-14 — — EP disclosed
WO-2009067419-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-28 — — WO disclosed
WO-2009067419-A1 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-28 — — WO disclosed
US-20090023155-A1 Polyelectrolyte multilayer films at liquid-liquid interfaces and methods for providing and using same WISCONSIN ALUMNI RESEARCH FOUNDATION 2009-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 HTR2A 1397/4885HSD17B10 2440/4885KDM4E 1915/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 HTR2A 1397/4885HSD17B10 2440/4885KDM4E 1915/4885
US-20110095269-A1 ELECTROACTIVE MATERIALS NAT1, ADRA1D, ADRA1B HTR2A 1453/4885HSD17B10 835/4885KDM4E 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.