Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600061 | 0.97 | ACE (0.51) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600156 | 0.90 | ACE (0.41) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600157 | 0.90 | ACE (0.41) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600081 | 0.89 | REN (0.46) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600067 | 0.88 | ACE (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL5570183 | 0.88 | ACE (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600080 | 0.86 | REN (0.45) | ACERENACE2KDM4EF2 | |
| SCHEMBL14600082 | 0.86 | REN (0.45) | ACERENACE2KDM4EF2 | |
| SCHEMBL5569928 | 0.86 | REN (0.45) | ACERENACE2KDM4EF2 | |
| SCHEMBL5566563 | 0.85 | ACE (0.53) | ACERENACE2KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663127-B2 | SKIN CARE COMPOSITION | PROCTER & GAMBLE (US) | 2017-02-15 | — | — | EP | disclosed |
| EP-1663127-B1 | SKIN CARE COMPOSITION | PROCTER & GAMBLE (US) | 2013-04-24 | — | — | EP | disclosed |
| US-7723529-B2 | Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7723529-B2 | Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | disclosed |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | disclosed |
| EP-1778617-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NicOx S.A. (FR) | 2007-05-02 | — | — | EP | disclosed |
| US-7169805-B2 | Captopril derivatives | NICOX S.A. (FR) | 2007-01-30 | — | — | US | disclosed |
| US-7169805-B2 | Captopril derivatives | NICOX S.A. (FR) | 2007-01-30 | — | — | US | disclosed |
| EP-1663127-A2 | SKIN CARE COMPOSITION | The Procter & Gamble Company (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2006008196-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NICOX S.A. (FR) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005025522-A2 | SKIN CARE COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20050053561-A1 | Hydrophilic gelling agent; nonionic surfactant comprising polysorbates, polyoxyalkylene hydrogenated castor oil, polyglycerin alkyl esters, polyoxyethylene sterols, and polyoxyethylene hydrogenated sterols; lower alcohol and water; sunscreen agents; nontacky, nongreasy feel | THE PROCTER & GAMBLE COMPANY | 2005-03-10 | — | — | US | disclosed |
| US-20040259808-A1 | Captopril derivatives | NICOX S.A. (FR) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053561-A1 | Hydrophilic gelling agent; nonionic surfactant comprising polysorbates, polyoxyalkylene hydrogenated castor oil, polyglycerin alkyl esters, polyoxyethylene sterols, and polyoxyethylene hydrogenated sterols; lower alcohol and water; sunscreen agents; nontacky, nongreasy feel | LSS, LIPA, EBP | ACE 4670/4885REN 4438/4885ACE2 4730/4885 |
| US-20040259808-A1 | Captopril derivatives | REN, ACE, NPPA | ACE 2/4885REN 1/4885ACE2 4/4885 |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | OTUB1, TET1, TET3 | ACE 3389/4885REN 2027/4885ACE2 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.