Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | BCL6 | P41182 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533723 | 1.00 | PTPN11 (0.48) | PTPN11KDM1AGHSROGASCN9A | |
| SCHEMBL31513687 | 0.81 | MTOR (0.46) | KDM1AOGAMKNK1MKNK2EIF2AK4 | |
| SCHEMBL26120616 | 0.81 | MTOR (0.46) | KDM1AOGAMKNK1MKNK2EIF2AK4 | |
| SCHEMBL25240554 | 0.80 | PTPN11 (0.43) | PTPN11GHSRSCN9AROCK2ROCK1 | |
| SCHEMBL30457411 | 0.80 | PTPN11 (0.43) | PTPN11GHSRSCN9AROCK2ROCK1 | |
| SCHEMBL23579408 | 0.78 | KDM1A (0.42) | KDM1AOGAMKNK1MKNK2CDC7 | |
| SCHEMBL29959199 | 0.78 | KDM1A (0.42) | KDM1AOGAMKNK1MKNK2CDC7 | |
| SCHEMBL30068037 | 0.77 | ACACB (0.41) | KDM1AOGAMKNK1MKNK2SUV39H2 | |
| SCHEMBL25280102 | 0.77 | CTSS (0.42) | PTPN11GHSRROCK2ROCK1 | |
| SCHEMBL29631769 | 0.77 | KDM4E (0.44) | PTPN11GHSRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713978-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2010-05-11 | — | — | US | disclosed |
| EP-2013178-A1 | PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007113202-A1 | PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-10-11 | — | — | WO | disclosed |
| US-20070238737-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238737-A1 | NOVEL COMPOUNDS | FABP2, VIP, SLC10A2 | PTPN11 4363/4885KDM1A 4714/4885GHSR 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.