SCHEMBL3534017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3529435	0.80	KDM4E (0.46)	KDM4EHPGDCYP1A2NPC1CYP2D6
	SCHEMBL3538343	0.79	HPGD (0.43)	KDM4EHPGDCYP1A2NPC1CYP2D6
	SCHEMBL18329542	0.75	CA12 (0.47)	KDM4EHPGDMAPTKMT2ACA12
	SCHEMBL1506498	0.75	NLRP3 (0.40)	KDM4EHPGDCYP1A2NPC1CYP2D6
	SCHEMBL3205636	0.72	CA12 (0.44)	HPGDNPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL12407108	0.72	TUBB4A (0.50)	KDM4EHPGDCYP1A2NPC1CYP2D6
	SCHEMBL15108154	0.71	SMN1; SMN2 (0.63)	KDM4EHPGDNPC1RAB9ASMN1; SMN2
	SCHEMBL15233267	0.71	HPGD (0.55)	HPGDCYP1A2NPC1CYP2C9CYP2C19
	SCHEMBL11798134	0.69	NPC1 (0.58)	KDM4EHPGDNPC1RAB9ASMN1; SMN2
	SCHEMBL17666341	0.69	HPGD (0.53)	HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.