Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489594 | 1.00 | POLB (0.46) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL25878287 | 0.84 | SMN1; SMN2 (0.38) | CDK8CDK19HSP90AA1HSP90AB1LMNA | |
| SCHEMBL6582434 | 0.84 | ALDH1A1 (0.44) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL3546719 | 0.81 | POLB (0.63) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL23269424 | 0.80 | CFTR (0.38) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL3539265 | 0.78 | ALDH1A1 (0.51) | POLBLMNAMEN1KMT2AMAPT | |
| SCHEMBL14686091 | 0.76 | CDK8 (0.37) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL28491288 | 0.76 | CDK8 (0.47) | CDK8CDK19HSP90AA1HSP90AB1LMNA | |
| SCHEMBL22717021 | 0.76 | CDK8 (0.47) | POLBCDK8CDK19HSP90AA1HSP90AB1 | |
| SCHEMBL14353515 | 0.76 | POLB (0.69) | POLBCYP1A2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715412-B | Piperidinone herbicides | FMC公司 | 2019-11-26 | — | — | CN | disclosed |
| CN-106232594-B | Substituted 2-pyrimidinyl oxy benzene compound herbicide | FMC公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-107635974-A | 2- (phenoxy or phenylthio) pyrimidine derivatives as herbicides | 杜邦公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107531658-A | Butyrolactone as herbicides | 杜邦公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107250134-A | It is used as the substituted 2-pyrimidinyl oxy pyridine derivate of herbicide | 杜邦公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-106715412-A | Piperidinone herbicides | 杜邦公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106687452-A | Pyridones as herbicides | 纳幕尔杜邦公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106659159-A | Herbicidal triazoles | 杜邦公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106488913-A | Bis (aryl) catechol derivatives as herbicides | 纳幕尔杜邦公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106458926-A | Pyridazinone herbicides | 杜邦公司 | 2017-02-22 | — | — | CN | disclosed |
| US-7851638-B2 | Cyclohexanesulfonyl derivatives as GLYT1 inhibitors to treat schizophrenia | MERCK SHARP & DOHME LIMITED (GB) | 2010-12-14 | — | — | US | disclosed |
| US-20100029726-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME (UK) LIMITED (GB) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029726-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | GLRA1, GNMT, MGAT1 | POLB 4216/4885CDK8 4311/4885CDK19 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.