Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582434 | 0.86 | ALDH1A1 (0.44) | SMN1; SMN2HSP90AA1HSP90AB1KDM4EHSD17B10 | |
| SCHEMBL3536841 | 0.84 | POLB (0.46) | HSP90AA1HSP90AB1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29489594 | 0.84 | POLB (0.46) | HSP90AA1HSP90AB1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23269424 | 0.81 | CFTR (0.38) | HSP90AA1HSP90AB1KDM4EALDH1A1NPC1 | |
| SCHEMBL3539265 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2KMT2AKDM4ETP53HSD17B10 | |
| SCHEMBL2381068 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AKDM4ETP53HSD17B10 | |
| SCHEMBL6217742 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2HSP90AA1HSP90AB1KMT2AHSD17B10 | |
| SCHEMBL31214299 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2HSP90AA1HSP90AB1KMT2AKDM4E | |
| SCHEMBL9565873 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2HSP90AA1HSP90AB1KMT2AKDM4E | |
| SCHEMBL30586203 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2HSP90AA1HSP90AB1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | USP7, USP28, USP1 | SMN1; SMN2 2139/4885HSP90AA1 2316/4885HSP90AB1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.