SCHEMBL3537874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3535821	0.86	PTGER4 (1.00)	PTGER4FFAR1FFAR4MCL1
	SCHEMBL4687633	0.86	PTGER4 (0.56)	PTGER4MMP2MAOBRAB9AMMP13
	SCHEMBL3542072	0.84	PTGER4 (0.80)	PTGER4RAB9AFFAR1
	SCHEMBL27605346	0.77	PTGER4 (0.77)	PTGER4MAOBFFAR1MCL1
	SCHEMBL3532300	0.76	PTGER4 (1.00)	PTGER4HPGD
	SCHEMBL13302166	0.75	RAB9A (0.47)	PTGER4MAOBRAB9AALKBH1KDM4C
	SCHEMBL16841039	0.75	MAOB (0.72)	PTGER4MMP2MAOBRAB9AMMP13
	SCHEMBL7372943	0.74	MAOB (0.89)	MMP2MAOBRAB9AABCB1HPGD
	SCHEMBL3534872	0.73	PTGER4 (0.79)	PTGER4MMP2MMP13MMP3MMP1
	SCHEMBL22777827	0.72	PTGER4 (0.74)	PTGER4MMP2MMP9SMPD1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.