Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008806 | 0.98 | HRH3 (0.42) | CYP1A2CYP2D6HRH3PDE10APOLB | |
| SCHEMBL12151773 | 0.91 | PDE10A (0.43) | CYP1A2CYP2D6HRH3PDE10AL3MBTL1 | |
| SCHEMBL15447630 | 0.84 | HRH3 (0.40) | CYP1A2CYP2D6HRH3PDE10AL3MBTL1 | |
| SCHEMBL13548276 | 0.84 | CTSK (0.43) | CYP1A2HRH3L3MBTL1CTSKCTSS | |
| SCHEMBL13179354 | 0.83 | PDE10A (0.40) | CYP1A2CYP2D6HRH3PDE10AL3MBTL1 | |
| SCHEMBL21447803 | 0.83 | PDE10A (0.39) | CYP1A2CYP2D6HRH3PDE10AL3MBTL1 | |
| SCHEMBL22920033 | 0.82 | CYP19A1 (0.39) | L3MBTL1KDM4ESMN1; SMN2CYP19A1 | |
| SCHEMBL20401118 | 0.82 | L3MBTL1 (0.38) | PDE10AL3MBTL1KDM4ESMN1; SMN2IDO1 | |
| SCHEMBL20400983 | 0.82 | MERTK (0.42) | L3MBTL1KDM4ESMN1; SMN2IDO1CYP19A1 | |
| SCHEMBL13490624 | 0.81 | HRH3 (0.45) | CYP1A2CYP2D6HRH3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1680325-B | Preparation of pyridine derivatives | FUJIFILM FINE CHEMICALS CO LTD | 2011-05-25 | — | — | CN | disclosed |
| US-7723522-B2 | Pyridine derivative production method | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7723522-B2 | Pyridine derivative production method | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7723522-B2 | Pyridine derivative production method | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-1559711-B1 | PREPARATION OF PYRIDINE DERIVATIVES USING PYRIMIDINIUM DERIVATIVES AS INTERMEDIATES | FUJIFILM FINECHEMICALS CO LTD (JP) | 2008-06-25 | — | — | EP | disclosed |
| EP-1559711-B1 | PREPARATION OF PYRIDINE DERIVATIVES USING PYRIMIDINIUM DERIVATIVES AS INTERMEDIATES | FUJIFILM FINECHEMICALS CO LTD (JP) | 2008-06-25 | — | — | EP | disclosed |
| CN-1680325-A | Preparation of pyridine derivatives | SANKIO CHEMICAL CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-20050171355-A1 | Pyridine derivative production method | SANKIO CHEMICAL CO., LTD. | 2005-08-04 | — | — | US | disclosed |
| EP-1559711-A1 | PREPARATION OF PYRIDINE DERIVATIVES USING PYRIMIDINIUM DERIVATIVES AS INTERMEDIATES | Sankio Chemical Co., Ltd. (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171355-A1 | Pyridine derivative production method | CPS1, NAT1, ACMSD | CYP1A2 342/4885CYP2D6 270/4885HRH3 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.