Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097011 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL4529653 | 0.83 | MGAM (0.44) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL8577401 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL5001158 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL3142804 | 0.80 | SOAT1 (0.44) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL24834180 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL10611181 | 0.77 | SOAT1 (0.41) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL27617570 | 0.75 | SOAT1 (0.39) | ALDH1A1LMNAHSD17B10SOAT1TDP1 | |
| SCHEMBL22591704 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TDP1KMT2A | |
| SCHEMBL5755181 | 0.75 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10SOAT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829586-B2 | Aryl-substituted nitrogen-containing heterocyclic compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090275617-A1 | Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds | MSD K.K. (JP) | 2009-11-05 | — | — | US | disclosed |
| CN-101277932-A | Aryl-substituted nitrogen-containing heterocyclic compound | BANYU PHARMA CO LTD (JP) | 2008-10-01 | — | — | CN | disclosed |
| EP-1935881-A1 | ARYL-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275617-A1 | Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds | OPRL1, NPSR1, NPBWR1 | ALDH1A1 1623/4885LMNA 3162/4885HSD17B10 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.