SCHEMBL8577401

SCHEMBL8577401

CCOC(=O)C(CC(C)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
LMNA P02545 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
MMP8 P22894 1/20 0.39
GAA P10253 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
PIN1 Q13526 1/20 0.36
HPGD P15428 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097011 0.91 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL5001158 0.86 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL8917497 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL3538530 0.83 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL15015780 0.80 ALOX15 (0.46) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL30371946 0.78 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL663775 0.78 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL5755181 0.78 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10TDP1MEN1
SCHEMBL22591704 0.78 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10TDP1MEN1
Acetic Acid SCHEMBL4559166 0.77 MEN1 (0.52) ALDH1A1LMNAHSD17B10TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5777149-A Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts ROCHE VITAMINS INC. (US) 1998-07-07 US disclosed
US-5681977-A Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts ROCHE VITAMINS INC. (US) 1997-10-28 US disclosed
US-5631398-A Method for the production of (3-alkoxycarbonyl-2-butenyl) triphenylphosphonium salts ROCHE VITAMINS INC. (US) 1997-05-20 US disclosed
US-5502236-A Method for the production of (3-alkoxycarbonyl-2-butenyl)triphenylphosphonium salts HOFFMANN-LA ROCHE INC. (US) 1996-03-26 US disclosed