SCHEMBL354205

SCHEMBL354205

C=Cc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TSHR P16473 2/20 0.59
LTA4H P09960 5/20 0.57
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
TLR4 O00206 1/20 0.48
TLR2 O60603 1/20 0.48
TGM2 P21980 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SRD5A2 P31213 1/20 0.44
AKR1B1 P15121 1/20 0.44
HPGD P15428 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480540 0.94 ALDH1A1 (0.52) ALDH1A1TSHRLTA4HNR1H2BAX
Diphenylether SCHEMBL787546 0.93 TSHR (0.70) ALDH1A1TSHRLTA4HNR1H2BAX
Diphenylether SCHEMBL27852840 0.91 TSHR (0.67) ALDH1A1TSHRLTA4HNR1H2BAX
Diphenylether SCHEMBL28210841 0.91 TSHR (0.67) ALDH1A1TSHRLTA4HNR1H2BAX
SCHEMBL296908 0.90 ALDH1A1 (0.65) ALDH1A1TSHRLTA4HNR1H2BAX
SCHEMBL19131747 0.89 ALDH1A1 (0.58) ALDH1A1TSHRLTA4HMAOATLR4
SCHEMBL9513816 0.86 ALDH1A1 (0.59) ALDH1A1TSHRLTA4HNR1H2BAX
SCHEMBL18381157 0.85 FFAR4 (0.48) ALDH1A1TSHRLTA4HNR1H2BAX
SCHEMBL17445756 0.83 ALDH1A1 (0.55) ALDH1A1TSHRLTA4HTLR4TLR2
SCHEMBL20024709 0.83 ALDH1A1 (0.55) ALDH1A1TSHRTLR4TLR2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 748 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-119775469-A Matrix resin, photoresist composition, photoresist and preparation method and application thereof 上海彤程电子材料有限公司 2025-04-08 CN claimed
CN-119504827-A Preparation method of alkenyl silane compound 中国科学院兰州化学物理研究所 2025-02-25 CN claimed
CN-119039195-A Preparation method of beta-thiocyanate alcohol derivative 山东省分析测试中心 2024-11-29 CN claimed
EP-3532898-B1 METHOD FOR PRODUCING A POLYMER BY NITROXYL-CONTROLLED POLYMERISATION, AND POLYMER FRAUNHOFER GES FORSCHUNG (DE) 2024-07-31 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-114345370-B Method for reduction cross coupling of photocatalytic aromatic olefin and halogenated hydrocarbon 陕西师范大学 2023-07-21 CN claimed
CN-116444559-A Preparation method of (E) -alkenyl phosphine oxide derivative 安阳师范学院 2023-07-18 CN claimed
US-6657030-B2 High refractive index and hydrophilic monomers, a crosslinker, an initiator and water BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
US-6657032-B2 High refractive index and hydrophilic monomers, a crosslinker, an initiator and water BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP claimed
US-20020049290-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-25 US claimed
US-20020042483-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-11 US claimed
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 US claimed
US-20020037984-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-03-28 US claimed
US-6329485-B1 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2001-12-11 US claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed
EP-0625418-A1 RESIN MOLD-COVERING METHOD FOR MOLDED RESIN PRODUCTS, RESIN MOLD-COVERING APPARATUS EMPLOYED IN THE SAME METHOD, MATERIAL USED FOR THE SAME COVER-MOLDING, AND MOLDED PRODUCT FORMED BY THE SAME METHOD MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1994-11-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA ALDH1A1 1323/4885TSHR 1437/4885LTA4H 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.