Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542111 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR6FGFR1 | |
| SCHEMBL3538066 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR6CHRNA7 | |
| SCHEMBL3538063 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR6CHRNA7 | |
| Hydrochloric Acid SCHEMBL3537297 | 0.85 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR6CHRNA7 | |
| SCHEMBL3062717 | 0.80 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3HTR6NOS3 | |
| Bromide SCHEMBL8098518 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR6CHRNA7 | |
| Hydrochloric Acid SCHEMBL6498978 | 0.79 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3HTR6NOS3 | |
| SCHEMBL8108438 | 0.77 | HTR6 (0.50) | SLC6A2SLC6A4SLC6A3HTR6CHRNA7 | |
| SCHEMBL6492685 | 0.74 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR6NOS3 | |
| SCHEMBL7210034 | 0.73 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781456-B2 | Enantiomers of 3-heteroaryl-8H-8-azabicyclo(3.2.1)oct-2-ene and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2010-08-24 | — | — | US | disclosed |
| US-20080214820-A1 | Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors | NEUROSEARCH A/S (DK) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214820-A1 | Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors | SLC18A2, SLC6A2, SLC18A3 | SLC6A2 2/4885SLC6A4 7/4885SLC6A3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.