Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062717 | 0.84 | SLC6A4 (0.53) | HTR6SLC6A2SLC6A4SLC6A3NOS3 | |
| SCHEMBL2419033 | 0.83 | SLC6A2 (0.43) | HTR6SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL2419034 | 0.83 | SLC6A2 (0.43) | HTR6SLC6A2SLC6A4SLC6A3CHRNA7 | |
| Hydrochloric Acid SCHEMBL6498978 | 0.82 | SLC6A4 (0.52) | HTR6SLC6A2SLC6A4SLC6A3OPRM1 | |
| Cadaverine Tartrate SCHEMBL3542909 | 0.78 | SLC6A3 (0.48) | HTR6SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL3542115 | 0.77 | SLC6A2 (0.49) | HTR6SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL3542111 | 0.77 | SLC6A2 (0.49) | HTR6SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL6553385 | 0.77 | SLC6A4 (0.58) | HTR6SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL5829525 | 0.77 | SLC6A4 (0.58) | HTR6SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7210034 | 0.77 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |