SCHEMBL354227

SCHEMBL354227

Cc1ccc(C(N)=O)c(C)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT3 Q9NTG7 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NNMT P40261 3/20 0.41
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CLCN2 P51788 1/20 0.37
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
DGAT1 O75907 1/20 0.36
PARP1 P09874 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1776795 0.98 SIRT3 (0.44) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL1018603 0.90 NNMT (0.47) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL29889389 0.90 NNMT (0.47) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL3357139 0.82 SIRT3 (0.42) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL128133 0.82 SIRT3 (0.42) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL27614341 0.82 POLB (0.48) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL5354600 0.82 ERN1 (0.43) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL6235114 0.82 SIRT3 (0.42) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL7761691 0.82 TDP1 (0.42) SIRT3TDP1NNMTMKNK1MKNK2
SCHEMBL29625222 0.81 CYP1A2 (0.46) SIRT3TDP1NNMTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-116925082-A Polymorphic forms of 5H-pyrrolo [2,3-b ] pyrazine derivatives, methods of preparation and uses thereof 百济神州(苏州)生物科技有限公司 2023-10-24 CN claimed
CN-116925083-A Polymorphic forms of 5H-pyrrolo [2,3-b ] pyrazine derivatives, methods of preparation and uses thereof 百济神州(苏州)生物科技有限公司 2023-10-24 CN claimed
CN-108026077-B Phenoxymethyl derivatives 豪夫迈·罗氏有限公司 2021-11-05 CN claimed
CN-113195497-A Novel imidazopyrazine derivatives 豪夫迈·罗氏有限公司 2021-07-30 CN claimed
US-20200230128-A1 PHARMACEUTICAL COMPOSITIONS CHARLESTON LABORATORIES, INC. 2020-07-23 US claimed
CN-111040054-A Catalyst component for olefin polymerization, preparation method, catalyst and application thereof 中国石油化工股份有限公司 2020-04-21 CN claimed
EP-3237418-B1 TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2019-01-30 EP claimed
EP-3423041-A1 PHARMACEUTICAL COMPOSITIONS Charleston Laboratories, Inc. (US) 2019-01-09 EP claimed
US-20030235543-A1 Topical administration of pharmacologically active bases for skin lightening MAIBACH HOWARD I (US) 2003-12-25 US claimed
US-20030235627-A1 Topical administration of pharmacologically active bases in the treatment of warts TECHNOLOGY RECOVERY SYSTEMS, LLC 2003-12-25 US claimed
US-20030235626-A1 Topical administration of pharmacologically active bases in the treatment of inflammatory dermatoses TECHNOLOGY RECOVERY SYSTEMS, LLC 2003-12-25 US claimed
WO-2003068230-A1 SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE PHARMACIA CORPORATION (US) 2003-08-21 WO claimed
US-20030099678-A1 Method and topical formulation for treating skin conditions associated with aging TECHNOLOGY RECOVERY SYSTEMS, LLC 2003-05-29 US claimed
US-20030077301-A1 Topical pharmaceutical composition for the treatment of inflammatory dermatoses DERMATRENDS, INC. 2003-04-24 US claimed
US-20030072814-A1 Topical pharmaceutical composition for the treatment of warts DERMATRENDS, INC. 2003-04-17 US claimed
US-20030072724-A1 Topical pharmaceutical composition to treat hyperpigmentation of the skin MAIBACH HOWARD I (US) 2003-04-17 US claimed
WO-2003026680-A2 METHOD AND TOPICAL FORMULATION FOR TREATING SKIN CONDITIONS ASSOCIATED WITH AGING DERMATRENDS, INC. (US) 2003-04-03 WO claimed
US-20030059450-A1 Method and topical formulation for treating skin conditions associated with aging MAIBACH HOWARD I (US) 2003-03-27 US claimed