Aniline

Aniline

SCHEMBL3543183

C1CCCCC1.Nc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.79
CYP3A4 P08684 5/20 0.53
TDP1 Q9NUW8 2/20 0.53
TAAR1 Q96RJ0 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAOA P21397 5/20 0.46
MAOB P27338 4/20 0.46
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
HTT P42858 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
PKM P14618 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL7723094 1.00 TSHR (0.79) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL30876135 0.89
SCHEMBL18517570 0.89 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL29395910 0.89
Aniline SCHEMBL11811648 0.89 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL16922171 0.89
Aniline SCHEMBL9755597 0.89 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL11803 0.89
SCHEMBL22096536 0.89 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL30471194 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106932568-B A kind of preparation method based on interface transform electrochemical luminescence immunosensor 济南大学 2019-04-23 CN claimed
CN-106932568-B A kind of preparation method based on interface transform electrochemical luminescence immunosensor 济南大学 2019-04-23 CN disclosed
CN-1547870-B Light emitting apparatus and electronic device SEIKO EPSON CORP 2011-01-19 CN disclosed
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2010-12-16 US disclosed
US-7795283-B2 Oxadiazole derivative as DGAT inhibitors ASTRAZENECA AB (SE) 2010-09-14 US disclosed
CN-100499075-C Electroluminescence device, method of manufacturing electroluminescence device, and electronic apparatus SEIKO EPSON CORP (JP) 2009-06-10 CN disclosed
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors ASTRAZENECA AB (SE) 2008-04-24 US disclosed
EP-1833806-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS AstraZeneca AB (SE) 2007-09-19 EP disclosed
CN-1941358-A Circuit substrate, electro-optical device and electronic apparatus SEIKO EPSON CORP (JP) 2007-04-04 CN disclosed
CN-1897252-A Electroluminescence device, method of manufacturing electroluminescence device, and electronic apparatus SEIKO EPSON CORP (JP) 2007-01-17 CN disclosed
CN-1873969-A Circuit board, electro-optical device, and electronic apparatus SEIKO EPSON CORP (JP) 2006-12-06 CN disclosed
CN-1278786-C Liquid material ejecting method and device, electro-optical device, and method for manufacturing substrate thereof SEIKO EPSON CORP (JP) 2006-10-11 CN disclosed
CN-1827234-A Jetting method of liquid, jetting apparatus of liquid, production method of substrate for electro-optical apparatus and production method of electro-optical apparatus SEIKO EPSON CORP (JP) 2006-09-06 CN disclosed
CN-1268000-C Circuit board, electro-optical device, and electronic apparatus SEIKO EPSON CORP (JP) 2006-08-02 CN disclosed
WO-2006064189-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2006-06-22 WO disclosed
CN-1547870-A Light emitting apparatus and electronic device ������������ʽ���� 2004-11-17 CN disclosed
CN-1472014-A Liquid material ejecting method and device, electro-optical device, and method for manufacturing substrate thereof ������������ʽ���� 2004-02-04 CN disclosed
CN-1435804-A Circuit board, electro-optical device, and electronic apparatus SEIKO EPSON CORP (JP) 2003-08-13 CN disclosed
CN-1009006-B Thermosetting resin composition, and prepreg and laminated sheet material produced from the same HITACHI LTD (JP) 1990-08-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS DGAT1, DGAT2, GPR119 TSHR 1451/4885CYP3A4 551/4885TDP1 4089/4885
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors DGAT1, DGAT2, GPR119 TSHR 1169/4885CYP3A4 544/4885TDP1 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.