Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10883684 | 1.00 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL95025 | 1.00 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL6058234 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL10975339 | 0.93 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL4584964 | 0.92 | ALDH1A1 (0.56) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL6246058 | 0.90 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL687626 | 0.86 | CYP3A4 (0.59) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| Bicarbonate SCHEMBL5705252 | 0.86 | CYP3A4 (0.59) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL10774925 | 0.83 | LMNA (0.52) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL12047841 | 0.83 | LMNA (0.52) | CYP3A4TSHRTDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554397-B | Negative electrode binder of lithium battery and preparation method thereof | 深圳市德泰能源有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119823639-A | UV (ultraviolet) curing coating and preparation method and application thereof | 浙江安益新材料有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119661755-A | Low-odor polyvinyl chloride resin and preparation method thereof | 中国石油化工股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118516047-A | Ultralow-temperature bonding double-layer anisotropic conductive adhesive film and preparation method and application thereof | 宁波连森电子材料有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118280855-A | Binding method of anisotropic conductive adhesive film with enhanced low-temperature indentation at low temperature | 宁波连森电子材料有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-110563871-B | Production device and preparation method of EVA raw material for photovoltaic adhesive film | 江苏斯尔邦石化有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118184851-A | Energy-saving and environment-friendly vinyl chloride-vinyl acetate copolymer paste resin and preparation method thereof | 沈阳化工股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118085178-A | Vinyl acetate-ethylene copolymer emulsion with high grafting rate and preparation method thereof | 中国石油化工股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117924134-A | Method for preparing di (2-ethylhexyl) peroxydicarbonate by one-step method and application thereof | 鄂尔多斯市瀚博科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117866398-A | High-strength high-toughness full-biodegradable material, preparation method and application | 安徽金普瑞新材料有限公司 | 2024-04-12 | — | — | CN | claimed |
| EP-2010484-A1 | PROCESS FOR SYNTHESIZING SELECTED ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2009-01-07 | — | — | EP | claimed |
| WO-2007125091-A1 | PROCESS FOR SYNTHESIZING SELECTED ORGANIC PEROXIDES | ARKEMA FRANCE (FR) | 2007-11-08 | — | — | WO | claimed |
| EP-1265938-A1 | OPTICAL RESIN COMPOSITION | PPG Industries Ohio, Inc. (US) | 2002-12-18 | — | — | EP | claimed |
| WO-2001036506-A1 | OPTICAL RESIN COMPOSITION | PPG INDUSTRIES OHIO, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| WO-2001014459-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2001-03-01 | — | — | WO | claimed |
| WO-2000031149-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | claimed |
| WO-2000031165-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | claimed |
| EP-0659194-A1 | PROCESS FOR (CO)POLYMERIZING VINYL MONOMERS. | KAYAKU NOURY CORP (JP) | 1995-06-28 | — | — | EP | claimed |
| WO-1994006269-A1 | PROCESS FOR (CO)POLYMERIZING VINYL MONOMERS | KAYAKU AKZO CORPORATION (JP) | 1994-03-17 | — | — | WO | claimed |
| US-4371677-A | Process for making dispersion copolymers through monomer metering | THE B.F. GOODRICH COMPANY (US) | 1983-02-01 | — | — | US | claimed |