Bicarbonate

Bicarbonate

SCHEMBL5705252

CCCCC(CC)COOCC(CC)CCCC.O=C(O)O.O=C(O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.59
TSHR P16473 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 6/20 0.51
CA2 P00918 4/20 0.51
RECQL P46063 1/20 0.49
MAPK1 P28482 3/20 0.47
LMNA P02545 3/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP14 P50281 1/20 0.46
HSD17B10 Q99714 1/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL687626 1.00 CYP3A4 (0.59) CYP3A4TSHRTDP1ATML3MBTL1
Bicarbonate SCHEMBL27521050 0.90 CA2 (0.58) CYP3A4TSHRTDP1ATML3MBTL1
SCHEMBL9663040 0.90 CYP3A4 (0.54) CYP3A4TSHRTDP1ATML3MBTL1
Tert-Butyl Hydroperoxide SCHEMBL27837151 0.89 CYP3A4 (0.50) CYP3A4TSHRTDP1ATML3MBTL1
SCHEMBL5198521 0.89 CYP3A4 (0.59) CYP3A4TSHRTDP1ATML3MBTL1
SCHEMBL1898541 0.86 CYP3A4 (0.54) CYP3A4TSHRTDP1ATML3MBTL1
Bicarbonate SCHEMBL10883684 0.86 CYP3A4 (0.58) CYP3A4TSHRTDP1ATML3MBTL1
Bicarbonate SCHEMBL95025 0.86 CYP3A4 (0.58) CYP3A4TSHRTDP1ATML3MBTL1
Bicarbonate SCHEMBL35433 0.86 CYP3A4 (0.58) CYP3A4TSHRTDP1ATML3MBTL1
Bicarbonate SCHEMBL28392070 0.86 CYP3A4 (0.50) CYP3A4TSHRTDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 US claimed
EP-4127017-A1 CYCLIC ETHER-ANHYDRIDE PHOTOPOLYADDITION AND USES THEREOF Université de Haute-Alsace (FR) 2023-02-08 EP claimed
US-20210363286-A1 Ultrafast Cyclic Ether-Amine Photopolyaddition And Uses Thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2021-11-25 US claimed
WO-2021191237-A1 CYCLIC ETHER-ANHYDRIDE PHOTOPOLYADDITION AND USES THEREOF UNIVERSITÉ DE HAUTE-ALSACE (FR) 2021-09-30 WO claimed
EP-3856819-A1 ULTRAFAST CYCLIC ETHER-AMINE PHOTOPOLYADDITION AND USES THEREOF Université de Haute Alsace (FR) 2021-08-04 EP claimed
WO-2020064839-A1 ULTRAFAST CYCLIC ETHER-AMINE PHOTOPOLYADDITION AND USES THEREOF UNIVERSITÉ DE HAUTE-ALSACE (FR) 2020-04-02 WO claimed
EP-3628697-A1 ULTRAFAST CYCLIC ETHER-AMINE PHOTOPOLYADDITION AND USES THEREOF Université de Haute Alsace (FR) 2020-04-01 EP claimed
WO-2016166470-A1 METHOD FOR DUAL PHOTOCHEMICAL/THERMAL CROSSLINKING ACTIVATABLE UNDER UV/VISIBLE IRRADIATION, AND COMPOSITION FOR IMPLEMENTING SAID METHOD UNIVERSITÉ DE HAUTE-ALSACE (FR) 2016-10-20 WO claimed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 US disclosed
EP-4127017-A1 CYCLIC ETHER-ANHYDRIDE PHOTOPOLYADDITION AND USES THEREOF Université de Haute-Alsace (FR) 2023-02-08 EP disclosed
CN-112888718-B Polymaleimide composition and process for producing the same KI化成股份有限公司 2023-01-31 CN disclosed
CN-115335452-A Curable composition and cured product 综研化学株式会社 2022-11-11 CN disclosed
CN-108227417-B Toner and image forming apparatus 佳能株式会社 2022-03-29 CN disclosed
CN-106953068-B Electrode active material, electrode and secondary battery including the same, and method of preparing the same 三星电子株式会社 2021-11-26 CN disclosed
EP-0123364-B1 VINYL CHLORIDE POLYMERS STAMICARBON B.V. (NL) 1989-08-02 EP disclosed
EP-0124176-B1 VINYL CHLORIDE POLYMERS STAMICARBON B.V. (NL) 1989-01-04 EP disclosed
EP-0106991-B1 PROCESS FOR PREPARING COPOLYMERS OF MONOETHYLENICALLY UNSATURATED MONO- AND DICARBOXYLIC ACIDS (ANHYDRIDE) BASF Aktiengesellschaft (DE) 1987-05-13 EP disclosed
EP-0124176-A1 Vinyl chloride polymers STAMICARBON B.V. (NL) 1984-11-07 EP disclosed
EP-0123364-A1 Vinyl chloride polymers STAMICARBON B.V. (NL) 1984-10-31 EP disclosed
US-4393185-A EPOXIDES CIBA-GEIGY CORPORATION (US) 1983-07-12 US disclosed