Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | HRH1 | P35367 | 1/20 | 0.68 |
| ▸ | SCN1A | P35498 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.68 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 5/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306732 | 0.85 | MEN1 (0.68) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL7442875 | 0.84 | CYP2D6 (0.66) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL2309661 | 0.83 | MEN1 (0.65) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL7324294 | 0.82 | MEN1 (0.73) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL10459095 | 0.82 | CYP2D6 (0.64) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL3823426 | 0.82 | MEN1 (0.58) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL9786895 | 0.81 | MEN1 (0.68) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL8472241 | 0.81 | HRH1 (0.68) | MEN1LMNACYP2D6HRH1SCN1A | |
| Azacyclonol SCHEMBL241817 | 0.81 | HRH1 (1.00) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL8791454 | 0.80 | MEN1 (0.57) | MEN1LMNACYP2D6HRH1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231551-A1 | COMPOSITIONS AND USES THEREOF | UNIVERSITY OF VIRGINIA | 2020-07-23 | — | — | US | disclosed |
| US-7683070-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-7300946-B2 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | BAYER CROPSCIENCE AG (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | FMC CORPORATION | 2006-06-22 | — | — | US | disclosed |
| EP-0912090-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORP (US) | 2000-05-17 | — | — | EP | disclosed |
| US-6017931-A | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines | FMC CORPORATION | 2000-01-25 | — | — | US | disclosed |
| EP-0912090-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORPORATION (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5795901-A | Insecticidal N-(substituted arylmethyl)-4- bis(substituted aryl)hydroxymethyl!piperidinium salts | FMC CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |
| WO-1998000015-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED ARYL) HYDROXYMETHYL]PIPERIDINIUM SALTS | FMC CORPORATION (US) | 1998-01-08 | — | — | WO | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5569664-A | AGRICULTURAL INSECTICIDES | FMC CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231551-A1 | COMPOSITIONS AND USES THEREOF | CYP11B2, NQO1, CYP11B1 | MEN1 146/4885LMNA 1499/4885CYP2D6 188/4885 |
| US-20060135504-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | MEN1 2174/4885LMNA 2216/4885CYP2D6 541/4885 |
| US-20080090828-A1 | N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines | DDT, DRD4, QDPR | MEN1 2020/4885LMNA 2194/4885CYP2D6 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.