Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544272 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 | |
| SCHEMBL7787413 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10CFTRMAPT | |
| SCHEMBL8413968 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10CFTRMAPT | |
| SCHEMBL20880393 | 0.74 | PTGS1 (0.40) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 | |
| SCHEMBL3550755 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTP2RX1 | |
| SCHEMBL3037744 | 0.66 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 | |
| SCHEMBL30371054 | 0.66 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 | |
| SCHEMBL14090840 | 0.64 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 | |
| SCHEMBL14090843 | 0.63 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10CFTRMAPT | |
| SCHEMBL19187531 | 0.63 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10CFTRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-08-24 | — | — | US | claimed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | claimed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | claimed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | claimed |
| US-7652059-B2 | 1-methyl-4-trifluoromethyl-1H-pyrrole-3-carboxylic acid [2-(1,3-dimethylbutyl)phenyl]amide; protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | disclosed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-08-24 | — | — | US | disclosed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | disclosed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | CBR3, PYCR1, CBR1 | ALDH1A1 3130/4885KDM4E 787/4885HSD17B10 2358/4885 |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | CBR3, CTH, PYCR1 | ALDH1A1 3612/4885KDM4E 1354/4885HSD17B10 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.